Personalized Health

  1. Arterial Stiffness, Genetic Risk, and Type 2 Diabetes: A Prospective Cohort Study. Wang M, Huang J, Wu T, Qi L. Diabetes Care. 2022 Jan 25:dc211921.
  2. Healthy Sleep Patterns and Risk of Incident Arrhythmias. Li X, Zhou T, Ma H, Huang T, Gao X, Manson JE, Qi L. J Am Coll Cardiol. 2021 Sep 21;78(12):1197-1207.
  3. Obesity and the relation between joint exposure to ambient air pollutants and incident type 2 diabetes: A cohort study in UK Biobank. Li X, Wang M, Song Y, Ma H, Zhou T, Liang Z, Qi L. PLoS Med. 2021 Aug 30;18(8):e1003767.
  4. Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease. Wang N, Sun Y, Zhang H, Wang B, Chen C, Wang Y, Chen J, Tan X, Zhang J, Xia F, Qi L, Lu Y. Eur Heart J. 2021 Oct 21;42(40):4180-4188.
  5. Replacement of Sedentary Behavior by Various Daily-Life Physical Activities and Structured Exercises: Genetic Risk and Incident Type 2 Diabetes. Li X, Zhou T, Ma H, Liang Z, Fonseca VA, Qi L. `. 2021 Jun 28:dc210455. doi: 10.2337/dc21-0455..
  6. Joint exposure to various ambient air pollutants and incident heart failure: a prospective analysis in UK Biobank. Wang M, Zhou T, Song Y, Li X, Ma H, Hu Y, Heianza Y, Qi L. Eur Heart J. 2021 Apr 21;42(16):1582-1591.
  7. Adherence to a Healthy Sleep Pattern and Incident Heart Failure: A Prospective Study of 408 802 UK Biobank Participants. Li X, Xue Q, Wang M, Zhou T, Ma H, Heianza Y, Qi L. Circulation. 2021 Jan 5;143(1):97-99.
  8. Baseline Vitamin D Status, Sleep Patterns, and the Risk of Incident Type 2 Diabetes in Data From the UK Biobank Study. Wang M, Zhou T, Li X, Ma H, Liang Z, Fonseca VA, Heianza Y, Qi L. Diabetes Care. 2020 Nov;43(11):2776-2784.
  9. The Mediterranean diet, plasma metabolome, and cardiovascular disease risk. Li J, Guasch-Ferré M, Chung W, Ruiz-Canela M, Toledo E, Corella D, Bhupathiraju SN, Tobias DK, Tabung FK, Hu J, Zhao T, Turman C, Feng YA, Clish CB, Mucci L, Eliassen AH, Costenbader KH, Karlson EW, Wolpin BM, Ascherio A, Rimm EB, Manson JE, Qi L, Martínez-González MÁ, Salas-Salvadó J, Hu FB, Liang L. Eur Heart J. 2020 Jul 21;41(28):2645-2656. 1
  10. Long-Term Changes in Gut Microbial Metabolite Trimethylamine N-Oxide and Coronary Heart Disease Risk. Heianza Y, Ma W, DiDonato JA, Sun Q, Rimm EB, Hu FB, Rexrode KM, Manson JE, Qi L. J Am Coll Cardiol. 2020 Feb 25;75(7):763-772.

Multi-Omics

  1. Epigenomic and Transcriptomic Prioritization of Candidate Obesity-Risk Regulatory GWAS SNPs. Zhang X, Li TY, Xiao HM, Ehrlich KC, Shen H, Deng HW, Ehrlich M. Int J Mol Sci. 2022 Jan 23;23(3):1271.
  2. Multi-omics research in sarcopenia: Current progress and future prospects. Liu JC, Dong SS, Shen H, Yang DY, Chen BB, Ma XY, Peng YR, Xiao HM, Deng HW. Aging Res Rev. 2022 Jan 29;76:101576.
  3. Genome-wide meta-analysis of alcohol use disorder in East Asians. Zhou H, Kalayasiri R, Sun Y, Nuñez YZ, Deng HW, Chen XD, Justice AC, Kranzler HR, Chang S, Lu L, Shi J, Sanichwankul K, Mutirangura A, Malison RT, Gelernter J. Neuropsychopharmacology. 2022 Jan 29.
  4.  Single-cell RNA sequencing deconvolutes the in vivo heterogeneity of human bone marrow-derived mesenchymal stem cells. Wang Z, Li X, Yang J, Gong Y, Zhang H, Qiu X, Liu Y, Zhou C, Chen Y, Greenbaum J, Cheng L, Hu Y, Xie J, Yang X, Li Y, Schiller MR, Chen Y, Tan L, Tang SY, Shen H, Xiao HM, Deng HW. Int J Biol Sci. 2021 Oct 11;17(15):4192-4206.
  5. Accurate recognition of colorectal cancer with semi-supervised deep learning on pathological images. Yu G, Sun K, Xu C, Shi XH, Wu C, Xie T, Meng RQ, Meng XH, Wang KS, Xiao HM, Deng HW. Nat Commun. 2021 Nov 2;12(1):6311.
  6. A multi-ethnic whole genome sequencing study to identify novel loci for bone mineral density. Greenbaum J, Su KJ, Zhang X, Liu Y, Liu A, Zhao LJ, Luo Z, Tian Q, Shen H, Deng HW. Hum Mol Genet. 2021 Oct 21:ddab305.
  7. Polymorphisms of the TNF, LTA, and TNFRSF1B genes are associated with onsets of menarche and menopause in US women of European ancestry. Dvornyk V, Churnosov M, Deng HW. Ann Hum Biol. 2021 Aug;48(5):400-405.
  8. Novel strategy for disease risk prediction incorporating predicted gene expression and DNA methylation data: a multi-phased study of prostate cancer. Wu C, Zhu J, King A, Tong X, Lu Q, Park JY, Wang L, Gao G, Deng HW, Yang Y, Knudsen KE, Rebbeck TR, Long J, Zheng W, Pan W, Conti DV, Haiman CA, Wu L. Cancer Commun (Lond). 2021 Dec;41(12):1387-1397.

New Technology Development

  1. Rapid detection of multiple SARS-CoV-2 variants of concern by PAM-targeting mutations. Ning B, Youngquist BM, Li DD, Lyon CJ, Zelazny A, Maness NJ, Tian D, Hu TY. Cell Rep Methods. 2022 Feb 7:100173.
  2. Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma. Nature Nanotechnology. Ning B, Huang Z, Youngquist BM, Scott JW, Niu A, Bojanowski CM, Zwezdaryk KJ, Saba NS, Fan J, Yin XM, Cao J, Lyon CJ, Li CZ, Roy CJ, Hu TY. Nat Nanotechnol. 2021 Sep;16(9):1039-1044.
  3. A smartphone-read ultrasensitive and quantitative saliva test for COVID-19. Ning B, Yu T, Zhang S, Huang Z, Tian D, Lin Z, Niu A, Golden N, Hensley K, Threeton B, Lyon CJ, Yin XM, Roy CJ, Saba NS, Rappaport J, Wei Q, Hu TY. Sci Adv. 2021 Jan 8;7(2):eabe3703.
  4. Sensitive tracking of viral RNA in plasma through all stages of SARS-CoV-2 infection. Huang Z, Ning B, Yang HS, Youngquist BM, Niu A, Lyon CJ, Beddingfield BJ, Fears AC, Monk CH, Murrell AE, Bilton SJ, Linhuber JP, Norton EB, Dietrich ML, Yee J, Lai W, Scott JW, Yin XM, Rappaport J, Robinson JE, Saba NS, Roy CJ, Zwezdaryk KJ, Zhao Z, Hu TY. J Clin Invest. 2021 Apr 1;131(7):e146031.
  5. Extracellular Vesicle Tetraspanin-8 Expression Predicts Distant Metastasis in Non-Small Cell Lung Cancer after Concurrent Chemoradiation. Liu, Y., Fan, J., Xu, T., Ahmadinejad, N., Hess, K., Lin, S., Zhang, J., Liu, X., Liu, X., Ning, B., Liao, Z., Hu, TY. Sci Adv. 2020, 6:11, eaaz6162.
  6.  Rapid lipid-based normalization of membrane protein expression on extracellular vesicles in complex biological samples. Rodrigues, M., Richards, N., Ning, B., Lyon, C., Hu, TY. Nano Lett. 2019, 19, 11, 7623-7631 (Cover Story).
  7.  Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring. Liu, C., Zhao, Z., Fan, J., Lyon, C. J., Wu, H., Nedelokv, D., Zelazny, A.M., Olivier, K.N., Cazares, L.H., Holland, S.H., Graviss, E. A., Hu, TY. Proc. Natl. Acad. Sci. U S A. 2017, 114(15):3969-3974.
  8. Nanoplasmonic Quantification of Tumor-derived Extracellular Vesicles in Plasma Microsamples for Diagnosis and Treatment Monitoring. Liang K., Liu, F., Fan, J., Sun, D., Bernard, D. W., Li, Y., Yokoi, K., Katz, M. H., Koay, E. J., Zhao, Z., Hu, Y. Nat Biomed Eng. 2017;1:0021.  
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